Form: 10-Q

Quarterly report pursuant to Section 13 or 15(d)

EXHIBIT 32.1

Published on

EXHIBIT 32.1

CERTIFICATION PURSUANT TO RULE 13A-14(b) OR RULE 15D-14(b) OF THE SECURITIES
EXCHANGE ACT OF 1934 AND U.S.C. SECTION 1350

I, Michael A. Martino, President and Chief Executive Officer of Sonus
Pharmaceuticals, Inc. (the "Company"), certify, pursuant to Rule 13a-14(b) or
Rule 15d-14(b) of the Securities Exchange Act of 1934 and 18 U.S.C. Section
1350, that:

(1) the Quarterly Report on Form 10-Q of the Company for the quarterly
period ended March 31, 2004 (the "Report") fully complies with the
requirements of Section 13(a) or 15(d) of the Securities Exchange Act
of 1934 (15 U.S.C. 78m or 780(d)); and

(2) the information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations of
the Company.

Dated: April 21, 2004

/s/ Michael A. Martino
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Michael A. Martino
President and Chief Executive Officer